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SANT 2
CAS No. 329196-48-7
SANT 2( —— )
Catalog No. M33922 CAS No. 329196-48-7
SANT 2 is a Hedgehog (Hh) signaling pathway antagonist with potential anti-inflammatory and anticancer activity for the study of prostate, pancreatic and breast cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 37 | Get Quote |
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| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameSANT 2
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NoteResearch use only, not for human use.
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Brief DescriptionSANT 2 is a Hedgehog (Hh) signaling pathway antagonist with potential anti-inflammatory and anticancer activity for the study of prostate, pancreatic and breast cancer.
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DescriptionSANT 2 is a potent antagonist of Hh-signaling pathway. Hedgehog (Hh) signaling plays an important role in cell signaling of embryonic development and adult tissue homeostasis. SANT 2 has the potential for the research of several malignancies including Gorlin syndrome (a disorder predisposing to basal cell carcinoma, medulloblastoma and rhabdomyosarcoma), prostate, pancreatic and breast cancers.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetHedgehog (Hh)
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RecptorHedgehog/Smoothened
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Research Area——
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Indication——
Chemical Information
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CAS Number329196-48-7
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Formula Weight479.96
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Molecular FormulaC26H26ClN3O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (520.88 mM; Ultrasonic )
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SMILESO=C(NC=1C=CC(Cl)=C(C1)C2=NC=3C=CC=CC3N2)C4=CC(OCC)=C(OCC)C(OCC)=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Büttner A, et al. Synthesis and biological evaluation of SANT-2 and analogues as inhibitors of the hedgehog signaling pathway. Bioorg Med Chem. 2009 Jul 15;17(14):4943-54.?
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